The only time I would see it being pheasable for puting more than one instrument of different families, i.e. Flutes and Oboes, in the same staff is if you wrote a condensed score of which would be a non-transposing score. This would usually be a grand staff or two depending on the size of the ensemble.
To Gardener:
Horn players were changing crooks around the early 19th C. By the 20th C., horns had valves and could easily play chromatic passages, however, composers still wrote for horns in the old style, 1 and 3 were a similar range and 2 and 4 the same. Still in the non-transposed key of the piece. Therefore, hornists must transpose because the instrument was and still is in F.